Dr. Donna Albertson
Dr. Donna Albertson is Associate Director and Professor, Cancer
Research Institute and Professor, Department of Laboratory Medicine
at the University of California San Francisco. She received her
Ph.D. in Biochemistry from Harvard University. From 1981 to 1996,
she was a member of the scientific staff of the Medical Research
Council in the Molecular Genetics Unit and the Laboratory of Molecular
Biology, Cambridge, England. Dr. Albertson pioneered the development
of fluorescent in situ hybridization and its applications in single
copy gene mapping in the human and for mapping and expression analysis
in Caenorhabditis elegans. Recent work has focused on development
of microarray technology for measurement of DNA copy number alterations
and applications of this technology in medical genetics and studies
of genomic alterations in human cancers and mouse models of cancer.
Dr. Albertson has published over 100 peer reviewed articles and
reviews and holds a number of patents in the field of microarrays.
Recent Publications
Snijders, A.M., Nowak, N., Segraves, R., Blackwood, S., Brown,
N., Conroy, J., Hamilton, G., Hindle, A.K., Huey, B., Kimura, K.,
Law, S., Myambo, K., Palmer, J., Ylstra, B., Yue, J.P., Gray, J.W.,
Jain, A.N., Pinkel, D. and Albertson, D.G. 2001. Assembly of microarrays
for genome-wide measurement of DNA copy number by CGH. Nature Genet.
29, 263-264.
Snijders, A.M., Fridlyand, J., Mans, D.A., Segraves, R., Jain,
A.N., Pinkel, D. and Albertson, D.G. 2003. Shaping of tumor and
drug resistant genomes by instability and selection. Oncogene 22,
4370-4379.
Albertson, D. G. 2003. Profiling Breast Cancer by Array CGH. Breast
Cancer Res. Treat. 78, 289-298.
Albertson, D. G., Collins, C., McCormick, F. and Gray, J. W. 2003.
Chromosome aberrations in solid tumors. Nature Genet. 34, 369-376.
Albertson, D. G. and Pinkel, D. 2003. Genomic Microarrays in Human
Genetic Disease and Cancer. Hum. Mol. Genet. 12, R145-R152.
Fridlyand, J., Snijders, A. M., Pinkel, D., Albertson, D. G. and
Jain, A. N. 2004. Hidden Markov models approach to the analysis
of array CGH data. J. Multivariate Anal. 90, 132-153.
Snijders, A.N., Nowak, N. J., Huey, B., Fridlyand, J., Law, S.,
Conroy, J., Tokuyasu, T., Demir, K., Chiu, R., Mao, J.-H., Jain,
A.N., Jones, S.J.M., Balmain, A., Pinkel, D. and Albertson, D.G.
2005. Mapping segmental and sequence variations among laboratory
mice using BAC array CGH. Genome Res., 15, 302-311.
Snijders, A. M., Schmidt, B. L., Fridlyand, J., Dekker, N., Pinkel,
D., Jordan, R. C. K. and Albertson, D. G. 2005. Rare amplicons implicate
frequent deregulation of cell fate specification pathways in oral
squamous cell carcinoma. Oncogene advance online publication 11
April 2005; doi:10.1038/sj.onc.1208601.
|
 |
